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Gout Dugout.Issue #026.Can I get a uric acid reduction from Vitamin B5?; my uric acid test;
February 01, 2010

Welcome to the February 2010 issue of the Gout Dugout newsletter. A ten minute read that could give you a couple, or more, useful gout ideas.

A URIC ACID TEST - WHAT'S NORMAL?

There's a lot of theory in the world of gout treatment but here's a small story from the real gout world.

My doctor recently decided I needed a "full monty" blood test.(i.e. measurements of lots of blood substances) I had an operation in November last year and had been feeling fatigued. He didn't think the fatigue was connected to the op. Out came his blood tests form and he started ticking the tests I needed. Of course a uric acid test was at the front of my mind and he hadn't ticked it. I suggested it,he agreed. At my age - a just after World War 2 baby boomer who was a teenager in the 1960's - my uric acid may well have risen to a threatening level.

Off to a hospital where they took three small test tubes of blood - more than I expected.

A week later, when the results had come back, we discussed the numbers. The good news was that he thought everything was OK, but just one thing puzzled me. My uric acid level he said was OK. It was measured at 0.420 mmol/L, which is just over 7.0 mg/dL.

(mg/dL is used in the United States and mmol/L in most other countries). To convert to mg/dL, divide mmol/L by 59.4, or to get the mmol/L number, multiply the mg/dL figure by 59.4.

So what bothered me? The top of the normal range, according to the lab that analyzed the blood,was 0.510 mmol/L or 8.58 mg/dL. Now just about every gout expert I've ever read or spoken to - academic researchers, doctors, pharmaceutical manufacturers, uric acid test meter manufacturers - think that normal is 7.0 mg/dL (0.416mmol/L) if you are male, and around 6.0 mg/dL (0.356 mmol/L) if you are female.

Above these numbers and you could be heading for gout trouble especially above 9 or 10 mg/dL. So my uric acid level is touching the top end, according to most experts, and could be heading north into enemy territory over the next few years. But it's not above normal according to this lab. However, I think it's wiser for me to believe that 7.0 mg/dL is normal (the lower number), not 8.58 mg/dL (0.510 mmol/L).

In 2/3 months I shall be in a different country...in the Far East. I'll do the uric acid test again with a lab I've used before. I already know the lab in the Far Eastern country's top end of normal figure is 6.95 mg/dL for men and 5.6 mg/dL for women.

And one more thing about uric acid tests.......If you have successfully lost weight you know what an unpredictable process it often is. Another dieting week passes and you go on the bathroom scales. During the week you've turned down so many delightful tastes.If these were the scales of justice you'd be down 2lbs every week. But the weight is the same as a week earlier! Another time you go on the scales and you are 3lbs down. Uric acid tests are a bit like this, so look for reductions over time, just like weight loss.

WILL I ACHIEVE A URIC ACID REDUCTION WITH PANTOTHENIC ACID(VITAMIN B5)?

So now I have a hopefully accurate uric acid reading to be the base line, I am going to find out if Pantothenic acid will get me a uric acid reduction. Ten days ago I put up a new page describing everything I've found out so far about Pantothenic acid lowering uric acid levels. None other than Dr.Atkins said it did, reasonably reliably, in his book Dr.Atkins' Vita-Nutrient Solution.

Click here if you want to go to the Pantothenic acid page

I won't be on a low purine diet, or the Zone diet, just my usual 60-90 carbs a day diet (which goes down to 30-35 when I'm actually dieting). So there won't be any diet change. And I won't take a large amount of any of the other vitamins reported to lower uric acid,(UA) nor drink a massive amount of water, nor eat high pH foods. And I won't splurge on high ORAC score fruits and veg, because some of them may reduce uric acid a bit.

No baking soda (bicarbonate of soda), cherries, celery or apple cider vinegar. My exercise level will remain unchanged, and I'll record my weight when I start because falling weight can deliver a uric acid reduction too. I won't be on any lowering UA drugs.

In other words only Vitamin B5 should have the major effect. And I'll take other B vitamins as well, because B vitamins work better when they are taken together.

I'll take 800 mg daily in the form of calcium pantothenate, the amount and form of B5 Dr.Atkins' recommended for gout. Starting in early February for 3 months. After 3 months,I'll have another uric acid test done.I'll announce the results in the June issue of The Gout Dugout which will be in your email inbox on June 1,2 or 3.

And when it's over, the next test will be Vitamin C, probably at a high dose of 3,000mg (3 grams) daily.

KRYSTEXXA(PEGLOTICASE)-PROBABLY ON COURSE FOR FDA RE-FILING

I know a number of readers are waiting to see if Krystexxa will be approved. Krystexxa is for hard to treat gout cases (the medical word is refractory = stubborn). If you are the one of the gout sufferers who are waiting and hoping for Krystexxa (Pegloticase)approval from the U.S.FDA take note that in January its developers said they think they are on course to file again for FDA approval by the end of March this year. It's expected the FDA will decide within 6 months after filing.

The developers, Savient Pharmaceuticals, believe they are addressing the 2 concerns raised by the FDA - these were both about the manufacturing of Krystexxa, not about the medication's performance. However, Savient warned the FDA might require them to revisit these two issues yet again, and I think this might mean further delays if it happens. If it doesn't, expect a decision by the end of September this year.

CONTRIBUTIONS PAGES

People's real life experiences with their gout cures - and especially using a natural remedy for gout - are of terrific interest to other gout sufferers. Of course theories need to be understood before putting them into practice, but life is really about people and how they apply these natural remedy for gout theories. So if you have tried and succeeded in stopping gout flare ups, or if you've tried and failed, others want to hear how you did it. Why? Because for gout sufferers, gout is one of the biggest things in their lives and they want to beat it. They ARE interested.

With this firmly in mind I have added some contribution pages recently and will add more in the new few weeks. Do you have a useful gout experience to tell? You'll have a big audience for what you write. www.best-gout-remedies.com annual number of visitors from all over planet Earth would now need two very large sports stadiums to accomodate them all. No-body yet from Mars as far as I know, but maybe the Martians suffer gout too.

The contributions pages at present are:

http://www.best-gout-remedies.com/baking-soda-for-gout.html

http://www.best-gout-remedies.com/celery-for-gout.html

http://www.best-gout-remedies.com/cherry-juice-for-gout.html

http://www.best-gout-remedies.com/applecidervinegarforgout.html

NATIONAL NUTRIENT DATABASE UPDATED

The U.S.Department of Agriculture's National Nutrient Database for Standard Reference has been updated. It's now version SR22. It's free. If you had to pay for it you'd probably be spending about US$50. It's that good. I've used it for 3 years - it's fast and reliable. If only it showed the amounts of purines in foods, and significant nutrients like Quercetin and CoQ10. But most vitamins, minerals, fats, plus carbs and calories, and more besides, are there. If you want to download it (it can also be viewed online) there's a link on the free gout resources page

RECOGNITION FOR WWW.BEST-GOUT-REMEDIES.COM

I hadn't heard of www.KillerStartups.com until they emailed me last week saying best-gout-remedies.com was written up on their site because it's a "killer startup." I then found out this site gets a huge number of visitors so I guess it must be pretty good. BGR.com isn't actually a start up these days because I launched it in late June 2007.(The first pages went up in April 2007). And it gets a lot more visitors than they say. But it's always nice to get recognition.

FREE pH FOODS CHART

Paying attention to body alkalinity for treating gout is a big, under researched subject, although it has been a known gout treatment since at least the middle of the 19th century. I'll write more about it this year.

If you take the pH foods route to help lower uric acid levels, you have to know which foods have an alkaline effect and which have an acidic effect. The free pH foods chart and alkalizing recipes at www.phionbalance.com is worth using.Click on the following link and when the home page arrives, the download link for the chart is on the right. pHionbalance products

This site sells pH boosting products such as alkalizing water and minerals, antioxidant fruit supplements and pH test strips. All can play a role in lowering uric acid levels or improving body function. Become a member - it's free - and there are much better prices.

If you are not a subscriber to the Gout Dugout, this free monthly gout newsletter, you can sign up at this page.

Go to www.best-gout-remedies.com home page.

Next month, among other items, we'll look at a new gout drug, still in trials, that taken together with febuxostat achieved an enormous uric acid reduction - the biggest drop was down to 1.2 mg/dL in some healthy patients.

Thanks for reading, and all the best.

John Mepham BA (Hons)

165,Union Street, Maidstone, Kent, United Kingdom ME14 1EY

P.S. You may distribute this newsletter freely and free-of-charge, providing any links in it remain unchanged and it remains intact. Partial copying is not allowed.

NB. The contents of this newsletter contain medical information, not medical advice. Please always discuss gout remedies with a doctor or other health care professional before implementing any treatment.

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